Matthieu Louis

CRG, Matthieu Louis (ML)

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Scientific & Training Expertise: Matthieu Louis (ML) is a PI in the EMBL/CRG Systems Biology Program, a fruitful partnership between EMBL and CRG. ML has dual training in physics and biology. The Louis lab combines four fields of expertise: (i) computer-aided quantification of behaviour; (ii) statistical analysis of large datasets and integration of functional data into mathematical models; (iii) functional imaging, extracellular and intracellular recordings of the larval olfactory system; and (iv) engineering of new assays to quantify behavioural responses elicited by controlled stimuli. ML is also a Visiting Scientist of the HHMI-Janelia Farm Research Campus.

Training Expertise: ML supervises 3 graduate students, 2 postdocs and 3 technicians. The training expertise of  the Louis lab includes electrophysiology, molecular genetics, machine vision, behavioural quantification and computational modelling. 

Research & Training Environment: The CRG is an emerging first-class multidisciplinary research centre located in the Barcelona Biomedical Research Park (PRBB), a cluster for biomedical research in southern Europe which includes more than 1000 researchers. The CRG hosts cutting-edge core facilities and  has extensive expertise in promoting research excellence in a learning environment for graduate students and postdoctoral fellows. The CRG has an international PhD program (over 100 PhD students with 78% of foreign students) in partnership with the University Pompeu Fabra. CRG offers specific scientific/technology courses, a wide variety of internal seminars, and talks with international invited speakers. The PRBB offers to the campus community the INTERVALS programme ( to support the career development of researchers with complementary skills and the “Science meets Society” initiative to engage society in science and vice versa (see

Most relevant publications:

1. Gomez-Marin, A., Stephens, G. J., and M. Louis (2011). Active sampling and decision making in Drosophila chemotaxis.  Nature Communications 2:441

2. Louis, M., Huber, T., Benton, R., Sakmar, T. and L. B. Vosshall (2008). Bilateral olfactory sensory input enhances chemotaxis behavior. Nature Neuroscience 11:187-99

3. Fishilevich, E., Domingos, A.L., Asahina, K., Naef, F., Vosshall, L.B. and M. Louis (2005). Chemotaxis behavior mediated by single larval olfactory neurons in Drosophila. Current Biology 15:2086-2096