Good science, honest science - Research integrity workshop
Scientific journals, funding agencies and research institutions are becoming increasingly concerned about the quality of the research - in terms of good scientific practice - that they publish, fund or host.
This workshop refreshed our knowledge about the tangled topic of keeping science sound and honest. We discussed the latest thinking in responsible research conduct and learned how to analyse and manipulate images with integrity.
Responsible Conduct of Research: From Policy to Practice, Michele Garfinkel.
The responsible conduct of research encompasses a large variety of concepts, from how to choose a research project to how data are reported. Some principles of research integrity are universal. Some are highly specific to a particular research field. Many parameters of the responsible conduct of research contain culture-specific aspects that may make guidance difficult to generalize to all researchers.
In Europe, guidance and rules concerning research integrity are changing rapidly, and in some places being introduced for the first time. In this talk, I will provide a brief overview of the rationales and structures for guidance on responsible conduct of research. We will then together work through scenarios from several fields of research, including a structured analysis of stakeholders views with respect to research integrity. Finally, I will discuss current work in the research integrity community to illustrate how views of responsible conduct may change over time, and how decision-makers respond to such new information.
MICHELE S. GARFINKEL is the Manager of the Science Policy Programme at the European Molecular Biology Organization in Heidelberg, Germany. Her work focuses on societal concerns for the introduction of new biological technologies, scientific publishing, and the responsible conduct of research, approached primarily through technology assessment studies.
Acquiring and presenting reliable scientific imaging data – the Good, the Bad, the Ugly and the Downright Dishonest, Alison North.
Image manipulation is an all-too-frequent problem encountered by the editors of scientific journals. Manipulations to submitted images range from minor, inappropriate changes to blatantly fraudulent practices but all such changes can be classed as scientific misconduct. To complicate matters further, unreliable imaging data is frequently acquired in innocence simply due to insufficient understanding of the experimental manipulations and microscope set-up used. This workshop aims to clarify the difference between acceptable and unacceptable changes to scientific images and to present some of the common presentation guidelines established by top scientific journals. We will then examine some of the causes of unreliable imaging data, including poor specimen preparation or probe choice, incorrect microscope set-up and acquisition parameters, spherical and chromatic aberrations, light-induced artifacts and over-expression artifacts. We will examine the usefulness of the term “co-localization” in the modern era of super-resolution microscopy. Finally we will discuss good practices for appropriate image storage, image processing and image presentation regimes."
ALISON NORTH is the Senior Director of the Bio-Imaging Resource Center and a Research Associate Professor at the Rockefeller University (RU) in New York. Trained mainly in electron microscopy until she became hooked on live cell imaging, she now advises and trains hundreds of RU and external researchers in a wide variety of optical microscopy techniques. She was consulted by the editors of the Journal of Cell Biology (RU Press) when they established their guidelines for authors on image manipulation, and subsequently authored a JCB feature article entitled “Seeing is believing? A beginners’ guide to practical pitfalls in image acquisition”.
On the 6th of July this workshop was organized exclusively for the FLiACT students. Taking advantage of the presence of the speaker we repeated the workshop co-organized with Interval program at the science park PRBB where CRG is located. This allowed the participation of 39 researchers outside of the network.